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Gential Flow Filtration System - List of Manufacturers, Suppliers, Companies and Products

Gential Flow Filtration System Product List

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KrosFlo KR2i RPM System <Enhancing Process Control>

KrosFlo KR2i RPM System <Enhancing Process Control>

Achieve improved process control and efficiency, and reduce process risks!

The "KrosFlo KR2i RPM System" is a system that integrates real-time process management with lab-scale tangential flow filtration (TFF). This system combines the KrosFlo KR2i system with the CTech FlowVPX variable path length UV-Vis spectrophotometer, providing automated TFF with inline concentration monitoring and endpoint control. By combining the functionalities of KR2i and FlowVPX, it achieves improved process control and efficiency, as well as reduced process risks. 【Features】 ■ Enhances process control with high accuracy and reproducibility of results ■ Increases process efficiency by shortening cycle times and improving yields ■ Reduces process risks by ensuring accurate concentration in TFF processes *For more details, please download the PDF or feel free to contact us.

  • Filtration Equipment

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KrosFlo KR2i RPM System <Managing UF/DF Process>

KrosFlo KR2i RPM System <Managing UF/DF Process>

By shortening cycle time and improving yield rate, we will enhance the efficiency of the process!

We would like to introduce the "KrosFlo KR2i RPM System" tangential flow filtration system and inline protein concentration management. The "Tangential Flow Filtration (TFF) System" measures concentration during UF/DF operations. There is no longer a need to rely on offline fixed-length UV-Vis spectrophotometers. This system can measure protein concentration in real-time. 【Features】 ■ Simplified automated operation ■ Robust processing capability ■ Minimization of risk ■ Flexible configuration *For more details, please download the PDF or feel free to contact us.

  • Filtration Equipment

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Sartoflow Expert SU

Sartoflow Expert SU

Fully automated tangential flow filtration system using a closed-loop single-use system suitable for process development to pilot-scale manufacturing.

**Features** - Single-use TFF specifically designed for 1 to 20L scale, providing cost-effective solutions from process development to pilot. - Ready-to-use and closed system, resulting in low bio-burden risk. **Characteristics in ADC Manufacturing** - Automation of three processes: ADC synthesis, precipitate removal, and TFF within a single system. - Reduction of funding, labor, installation space, and process risks, enabling a seamless transition from process development to small-scale commercial ADC manufacturing. - Flexible process sequence control allows for compatibility with various ADC manufacturing protocols. - Stirring optimized for minimal capacity with temperature control.

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Sartoflow 1000

Sartoflow 1000

Efficient and scalable single-use tangential flow filtration system and automation process.

■ Design considering efficiency in the SUTFF application ■ Automation supporting advanced operations ■ Rapid exchange and cleanability of single-use flow kits maximize efficiency per batch

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Sartoflow 4500

Sartoflow 4500

An efficient and scalable single-use tangential flow filtration system through an automated process.

■ Design considering efficiency in the SUTFF application ■ Automation that supports advanced operations ■ User-friendly and quick setup

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KrosFlo KR2i RPM System

KrosFlo KR2i RPM System

Shorten cycle time! Improve process efficiency by enhancing yield rate.

We offer the "KrosFlo KR2i RPM System," which integrates real-time process management with lab-scale tangential flow filtration (TFF). This system combines the KrosFlo KR2i system with the CTech FlowVPX variable path length UV-Vis spectrophotometer, providing automated TFF with inline concentration monitoring and endpoint control. By combining the functionalities of KR2i and FlowVPX, we achieve improved process control and efficiency, as well as reduced process risks. 【Features】 ■ Enhances process control with high precision and reproducibility of results ■ Increases process efficiency by shortening cycle times and improving yield ■ Reduces process risks by ensuring accurate concentration in TFF processes *For more details, please download the PDF or feel free to contact us.

  • Other filtration and separation equipment

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KrosFlo RS 10 TFF Systems

KrosFlo RS 10 TFF Systems

By adding a valve, we expand filtration capacity and automate more process sequences!

We handle the "KrosFlo RS 10 TFF Systems." The "1/8 inch KrosFlo single-use tangential flow filtration (TFF) system" significantly improves product yield and operational efficiency through end-to-end (E2E) automation for bench-scale manufacturing. Additionally, the "ProConnex FlowPath" integrates advanced fluid management technologies such as injection molded tubing, pump heads, filters, and sensors into a single-use device. 【Filtration (TFF) System Components (partial)】 ■ Scale ■ Feed pump (maglev, diaphragm, or peristaltic pump) ■ Permeate side scale ■ Touch screen (21 inches) ■ Peristaltic pump (permeate control) *For more details, please download the PDF or feel free to contact us.

  • Filtration Equipment

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LV Centramate Tangential Flow Filtration System

LV Centramate Tangential Flow Filtration System

Scalable from lab scale up to a maximum of 4 L! Designed to maximize product recovery rate.

The "LV Centramate" is a product designed for the scale-up and scale-down of tangential flow filtration process development, small batch production of biopharmaceutical processes, scale-down testing, and the production of materials for safety and efficiency studies (Phase I clinical trials). With a low residual volume, it achieves high concentration factors from a small starting volume. Since it has the same flow path length as the Centramate cassette holder and Centrasette cassette holder, linear scale-up is possible. In a 2010 study, LV Centramate was used for the concentration of AAV viruses purified from cell culture supernatant [1]. 【Features】 ■ Linear scale-up is possible ■ Can also be used in conjunction with other lab TFF systems ■ Achieves high concentration factors from a small starting volume due to low residual volume ■ Easy connection with SUS316L polished luer lock ports, ensuring the same compatibility characteristics as the production scale Centrasette holder [1] Vandenberghe, et al., Human Gene Therapy. 21. 1251-1257 (2010).

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  • LV_CENTRAMATE_TFF_CASSETTE_OS100T12_Compressed.jpg
  • Minimate_EVO_System_LV_CENTRAMATE_500.jpg
  • Ultrafiltration

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Sartoflow SP

Sartoflow SP

Single-pass (SP) continuous tangential flow filtration

■Continuous Dialysis Filtration: Realizing Innovation The Sartocon SP cassette evolves traditional dialysis filtration into a single-pass system. ■Versatile System for Process Control It allows for the rapid establishment of process-specific parameters for continuous dialysis filtration. ■Intuitive Control Software With touch screen operation, complete and simple parameter control, and automation, it enables process control with constant TMP or constant feed flow rate.

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